7 comparative studies that show Medistim Transit Time Flow measurement improves CABG outcomes


Our curated collection of 7 comparative studies sheds light on the compelling advantages of incorporating Medistim Flow measurement technology into CABG procedures. Discover how TTFM enhances outcomes across a spectrum of metrics, including rates of Perioperative MI, MACE, reintervention rate, morbidity, mortality, and post-operative patency confirmed by angiography.

Explore the most recent study by Laali et al., “Impact of transit-time flow measurement on early postoperative outcomes in total arterial coronary revascularization with internal thoracic arteries.”  This study demonstrates a statistically significant reduction of MACE by more than 50%.


Read Laali et al. Study Here

Dive into the results of Kieser et al.’s study from 2010, which compares flow measurements with a PI value above or below 5, revealing a 68% reduction in the incidence of MACE.


Explore Kieser et al. Study Here

Discover the comprehensive study by Kim et al. from 2019 involving 2820 patients, highlighting how TTFM-guided revisions improved early arterial graft patency and reduced re-intervention.


Discover Kim et al. Study Here

Take the time to explore these studies and formulate your own informed opinion on how TTFM could elevate your CABG program. 



  1. Laali M, Nardone N, Demondion P, D’Alessandro C, Guedeney P, Barreda E et al. Impact of transit-time flow measurement on early postoperative outcomes in total arterial coronary revascularization with internal thoracic arteries: a propensity score analysis on 910 patients. Interact CardioVasc Thorac Surg Vol 35, Issue 2, Aug 2022. J Card Surg. 2022; 37: 4246-4253. DOI:10.1093/icvts/ivac065.
  2. Quan Z, Zhang X, Song X, Chen P and Wu Q. The use of intraoperative transit time flow measurement can reduce postoperative myocardial injury. DOI: 10.1111/jocs.16818
  3. Kim K-B, Choi JW, Oh SJ, Hwang HY, Kim SJ, Choi J-S & Lim C. Twenty-year experience with off-pump coronary artery bypass grafting and early postoperative angiography. Ann Thorac Surg 2020;109:1112-9. DOI: Published:September 06, 2019DOI: 10.1016/j.athoracsur.2019.07.053
  4. Becit N, Erkut B, Ceviz M, Unlu Y, Colak A and Kocak H. The impact of intraoperative transit time flow measurement on the results of on-pump coronary surgery. European Journal of Cardio-Thoracic Surgery 32 (2007) 313—318. DOI: 10.1016/j.ejcts.2007.04.037
  5. Bauer SF, Bauer K, Ennker IC, Rosendahl U and Ennker J. Intraoperative Bypass Flow Measurement Reduces the Incidence of Postoperative Ventricular Fibrillation and Myocardial Markers After Coronary Revascularisation. Thorac Cardiov Surg 2005; 53: 217–222. DOI: 10.1055/s-2005-837642
  6. Kieser TM, Rose S, Kowalewski R and Belenkie I. Transit-time flow predicts outcomes in coronary artery bypass graft patients: a series of 1000 consecutive arterial grafts. Eur J Cardiothorac Surg 2010;38:155-162. DOI: 10.1016/j.ejcts.2010.01.026
  7. Herman C, Sullivan JA, Buth K and Legare J-F. Intraoperative graft flow measurements during coronary artery bypass surgery predict in-hospital outcomes. Interact Cardiovasc Thorac Surg. 2008 Aug;7(4):582-5. doi: 10.1510/icvts.2008.175208. Epub 2008 May 8. PMID: 18467427.